Dave’s analysis has offered the inspiration for Apollo Neuroscience, an organization he co-founded in 2017 alongside his CEO spouse, Kathryn Fantauzzi. Apollo Neuroscience now affords the primary scientifically-validated wearable expertise that actively improves your well being utilizing a singular contact remedy that sends indicators of security to the mind. Customers of Apollo report having extra vitality, improved focus, enhanced rest, and higher sleep.

Along with Apollo, Dave can also be the co-founder and government director of The Board of Medication, a 501(c)(3) nonprofit dedicated to establishing peer-reviewed, evidence-based scientific tips for the manufacturing and secure use of at present unregulated various medicines, together with plant medicines. The Board of Medication gives coaching and certification to healthcare suppliers whereas setting high quality management requirements for complementary and various medicines, all to advertise high-quality scientific analysis, finest practices, and threat discount.

Alongside his scientific psychiatry apply, Dave is actively conducting analysis on the epigenetic regulation of trauma responses and restoration. His focus is to make clear the mechanism of psychedelic-assisted psychotherapy and the neurobiology of perception. His intensive analysis background contains incomes his MD in medication and a PhD in neuroscience from Albany Medical Faculty and specializing in psychiatry with a distinction in analysis at Western Psychiatric Institute & Clinic on the College of Pittsburgh Medical Heart.

Dave’s dedication to pushing the boundaries of neuroscience and his dedication to growing efficient various therapies make him a very fascinating visitor to host. On this dialog, Dave and I delve into how Apollo Neuro works and the science that underpins it, discover his analysis on neurotransmitters, and focus on the intriguing subject of MDMA remedy. So, should you’re excited by new frontiers of human well being, stress administration, and well-being, pay attention up!

Throughout our dialogue, you may uncover:

• Earlier podcast episode with Dr. David Rabin in regards to the Apollo:
• The Apollo is a next-generation wearable (use code BG15 to save lots of 15%)
  • It does not monitor the physique
  • It improves the physique’s well-being
  • Apollo can work alongside aspect the app or utterly unbiased of the cellphone
  • Activates mechanically after you save your schedule to the gadget
  • Regulates your circadian cycle for you
  • Has an airplane mode so as to flip off any EMF transmission whereas it’s operating
• Analysis began on the College of Pittsburgh in 2014
• Discovered methods to compose music for the physique, not for the ears
• Music calms us and clears our thoughts
• Apollo delivers that very same advantages by means of contact

-Combining Apollo with music…13:33

• Pairing the vibratory sensations with precise audio sensations
• The purpose is to create an ecosystem of well being 
• There are a lot of instruments that may assist however the Apollo mixed with music doubles the advantages
• Frequency of the Apollo matching the frequency of a sure soundtrack is coming quickly

-The science behind Apollo…16:50

• Early analysis on the College of Pittsburgh
  • How does music have an effect on the physique?
  • Is that impact translatable to haptics and contact?
• Enormous vary of vibrations that you just really feel all through your physique 200 hertz and under
• We really feel higher than we hear
• Some rhythms improve folks’s consciousness, readability, wakefulness, and vitality
• Different types of music are generally used for meditation and mindfulness apply
• Music has numerous impacts on the physique
• Biofeedback – breath and breath workouts research
• A meditative state begins between 5 and 7 breaths per minute
  • You’ll be able to measure that impact by means of the pores and skin with EKG
• Went one other step additional and measured
  • Brainwaves by means of EEG
  • Pupils
  • Bodily actions
  • Sweat
• Put 20 patterns to three folks after which gave them these actually hectic workouts to do cognitively
  • Requested them to charge the expertise and measured the outcomes
  • 2 of 20 vibrations offered 25% higher cognitive efficiency
  • Elevated HRV inside solely 3 minutes, immediately correlated with the rise in cognitive efficiency
  • Was in a position to develop a mathematical algorithm from that research
• The primary vibes found –
  • Vitality
  • Social
  • Focus
  • Energy nap
  • Get better
  • Calm 
  • Unwind
  • Go to sleep
• A second research on athletes found the Get better vibe
• Utilized what was found on different vibes and examined them on 300 folks for two years
• The distinction between the vibes
  • Velocity
  • Depth
  • Frequency and their modulation
  • The variations are supposed to be refined, not distractive

-How was Apollo made so small?…27:33

• Fitbit
• Whoop
• At first, not plenty of small choices
• Fairly a problem to search out the proper accomplice to do this sort of work
• Couple of years of looking
• Managed to search out the small motor that delivered vibration patterns faithfully
• Sensate (use code BGL to save lots of)
• Apollo can be utilized with a chest strap and clip
  • Can be worn wherever on the physique
• Sporting multiple
  • It might be extra immersive
  • Engaged on an app to regulate multiple gadget
• Apollo prices $349 (use code BG15 to save lots of 15%)

-The research of neurotransmitters and MDMA remedy…38:14

• Neurotransmitters are notoriously arduous and costly to check
• Denver VA is doing a really giant PTSD research of Apollo and 100 army veterans with PTSD
• Printed a paper displaying that MDMA-assisted remedy seems to reverse a few of the epigenetic trauma markers
• Traumatic occasions trigger adjustments to our stress response, all the way in which right down to epigenetics and cortisol receptors
• Three doses of MDMA in 12 weeks of psychotherapy in folks with extreme PTSD
  • Reverses their signs
  • Impacts the methylation of the cortisol receptor
• The trauma is saved within the physique all the way in which right down to our DNA and we will do issues to restore it
  • Learning that very same phenomenon within the research on the Denver VA
• Apollo was closely impressed by the understanding of how MDMA works in resolving trauma

-The Social mode in Apollo and MDMA remedy…41:21

• Ben’s expertise with MDMA remedy
• Apollo was designed to work equally (use code BG15 to save lots of 15%)
• Social mode helps folks really feel secure in social conditions
  • Prompts security response to the contact receptors in our pores and skin
• Transmits soothing vibrations to the emotional cortex of the mind
• MDMA is pointless
• Experimenting with Social mode

-Might Apollo detect the state you’re in and reply to it accordingly?…46:57

• Apollo got here from the thought to assist stress within the second
• In early days – working with folks within the labs, extreme autism spectrum dysfunction and, and panic dysfunction
  • Detected when these episodes have been going to occur earlier than turning into full-blown
• Coaching Apollo to detect sleep and assist folks get to sleep
• Apollo Labs – keep asleep function; first AI function for well being
• Oura Ring
• The purpose for the longer term – detect and study throughout the day and night time what you could be your finest self
• Wearable expertise that is listening to you and offering what you want
• Connecting Apollo with Oura Ring and Apple Well being
  • Proper now, Oura Ring and Apple Well being knowledge are used for analysis to construct options
  • Now delivering the primary AI for reducing disruptive sleep disturbances
  • 9 out of 10 folks complaining of insomnia within the U.S. expertise poor sleep as a result of they get up in the course of the night time and might’t fall again to sleep

-The outcomes of the sleep research…54:45

• Preliminary research of 582 folks, ultimately expanded to 1500
  • Individuals who have been utilizing Apollo and Oura Ring for years
• On common, have been utilizing Oura ring for eight months earlier than receiving an Apollo
  • Pre-Apollo baseline knowledge
  • Knowledge after receiving an Apollo
• Simply including Apollo confirmed a statistically vital enchancment in sleep
• Utilizing Apollo 3 hours a day, 5 days per week, 45-90 days is a candy spot
  • Confirmed half-hour improve in deep sleep (19%) and REM sleep (14%)
  • Lower in resting coronary heart charge and improve in HRV
• Ben’s Apollo energy nap routine
• Drops you into sleep fairly shortly and wakes you up gently
• Ben’s Apollo schedule
  • 9 p.m. – Unwind
  • 9:30 p.m. – Go to sleep
  • 6 a.m. – Vitality
  • 8 a.m. – Focus
  • 2 p.m. – Calm (for siesta)
  • Social and Get better mode each time he feels prefer it
• Battery life – on common 2-3 days
  • Working arduous to make battery life higher

-Research on athletes with Restoration perform…1:05:14

• A research was printed in July 2022 on the College of Pittsburgh
• A double-blind, randomized, placebo-controlled crossover research
• Apollo vibrations after intense train intervals
• Throughout a 2-minute restoration interval – will increase HRV
• Optimizes restoration and efficiency

-Stacking Apollo with different stuff…1:07:48

• The inspiration behind Apollo’s creation was breathwork and biofeedback
  • The rhythm of Apollo is that 5 to 7 breaths per minute that change over time that helps to get you right into a resonance state
• The most effective to pair respiratory with Apollo vibrations
  • Utilizing music and breathwork with Apollo (use code BG15 to save lots of 15%)
  • CBD
  • Temper-stabilizing adaptogens (consider the Apollo as an adaptogenic wearable)
  • “Higher with Apollo” program 
  • Combining Apollo with gentle sound stimulation machines
• BrainTap
• neuroVIZR (use code BEN10 to save lots of 10%)
• Dr. Rabin has additionally heard nice issues about folks combining Apollo with TRIPP VR and Oculus VR
• Apollo has been bettering the efficiency of video avid gamers in eSports
• Works properly on lengthy drives
• Bio-acoustic mat paired with the neuroVIZR (use code BEN10 to save lots of 10%)